Bisphenol A Diglycidyl Ether Induces Adipogenic Differentiation of Multipotent Stromal Stem Cells through a Peroxisome Proliferator–Activated Receptor Gamma-Independent Mechanism
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چکیده
منابع مشابه
Bisphenol A Diglycidyl Ether Induces Adipogenic Differentiation of Multipotent Stromal Stem Cells through a Peroxisome Proliferator–Activated Receptor Gamma-Independent Mechanism
BACKGROUND Bisphenol A (BPA) and bisphenol A diglycidyl ether (BADGE), used in manufacturing coatings and resins, leach from packaging materials into food. Numerous studies suggested that BPA and BADGE may have adverse effects on human health, including the possibility that exposure to such chemicals can be superimposed on traditional risk factors to initiate or exacerbate the development of ob...
متن کاملStability of bisphenol A diglycidyl ether and bisphenol F diglycidyl ether in water-based food simulants
Varnishes used for the inner coatings of food cans are often based on epoxy resins or vinylic organosols. The epoxy resins can be produced from bisphenol A (BPA) and bisphenol F (BPF), and these also contain bisphenol A diglycidyl ether (BADGE) or bisphenol F diglycidyl ether (BFDGE) as stabilising components. These compounds may break down during storage and also by the influence of food simul...
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BACKGROUND The introduction of specific BCR-ABL inhibitors in chronic myelogenous leukemia therapy has entirely mutated the prognosis of this hematologic cancer from being a fatal disorder to becoming a chronic disease. Due to the probable long lasting treatment with tyrosine-kinase inhibitors (TKIs), the knowledge of their effects on normal cells is of pivotal importance. DESIGN AND METHODS ...
متن کاملBisphenol A diglycidyl ether as a potential metabolic source of bisphenol A.
Epoxy resins find widespread use as adhesives and coatings in the construction and food industries. The majority of the products are based on resins that use bisphenol A diglycidyl ether (BADGE) as a precursor. This raises the question if BADGE could be a potential source of bisphenol A (BPA). The recent paper by Perez et al. (1) on the estrogenicity of BPA and some of its analogs and derivativ...
متن کاملHigh glucose induces adipogenic differentiation of muscle-derived stem cells.
Regeneration of mesenchymal tissues depends on a resident stem cell population, that in most cases remains elusive in terms of cellular identity and differentiation signals. We here show that primary cell cultures derived from adipose tissue or skeletal muscle differentiate into adipocytes when cultured in high glucose. High glucose induces ROS production and PKCbeta activation. These two event...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2012
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.1205063